Research Articles

Peer-reviewed studies distilled into actionable summaries. Updated daily.

Total: 67,602 articles • Showing 2 of 67,602
pubmed

Plasma proteomics defines two reproducible subphenotypes of sepsis-associated acute kidney injury with distinct outcomes.

Legrand M; Nguyen H; Calfee CS; Lu Y; Harhay M; Liu K; Chen D; Bernholz J; Matthay M; Mebazaa A; Pickkers P; Rojas E; Perez AR

Sepsis can hurt the kidneys, making it very dangerous for sick people. Scientists found two types of kidney problems in sepsis patients by looking at their blood proteins. They also found that a medicine works better for one type than the other.

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pubmed

A core transcriptional regulatory circuitry controls super-enhancer-driven activation of LGR5 in colorectal cancer.

Ye M; Wang S; Chen Y; Ma H; Ying Y; Ma W; Shi L; Ma C; Liu X; Wu W; Fordil B; Jia M; Geng R; Zhang X; Song X; Lin T; Wang M; Zhu WG; Shu XS

Scientists have found that a molecule called MYC plays a big role in how certain genes behave in colon cancer. They discovered that MYC works with other molecules to turn on important genes that help the cancer grow. This might help scientists find better ways to treat this kind of cancer.

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