pubmed
The RNA-binding protein HuR modulates the expression of the disease-linked rs1024611G-rs13900T haplotype.
Akhtar F; Ruiz JH; Liu YG; Resendez RG; Feliers D; Morales LD; Diaz-Badillo A; Lehman DM; Arya R; Alvarenga JCL; Blangero J; Duggirala R; Mummidi S
The study looks at a gene called CCL2 that affects diseases like HIV-related brain problems, tuberculosis, and heart disease. They found that a small part of the gene can change how much of it gets made, and this might change how sick a person gets. They also found that a protein called HuR sticks to this part and affects how the gene works.
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