Research Articles

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Total: 55,019 articles • Showing 2 of 55,019
pubmed

B cell expression of an enzymatic intermediary in ether lipid biosynthesis promotes antibody responses and germinal center size.

Cho SH; Jones MA; Meyer K; Anderson DM; Chetyrkin S; Calcutt MW; Caprioli RM; Semenkovich CF; Boothby MR

Researchers discovered that a specific enzyme, called PexRAP, is important for B cells to respond better to germs or vaccines. This enzyme helps B cells grow and survive by controlling certain chemicals inside them, leading to stronger and better immune responses.

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pubmed

Single-cell lineage tracing identifies hemogenic endothelial cells in the adult mouse bone marrow.

Feng JX; Yang MT; Li L; Li CC; Livak F; Chen J; Zhao Y; Wang D; Bhandoola A; Taylor N; Tosato G

Scientists studied special cells in adult mice to see if they can make blood cells like they do in young mice when developing. They found that these adult cells can still create new blood cells and help with body responses, just like when the mice were young.

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