Research Articles

Peer-reviewed studies distilled into actionable summaries. Updated daily.

Total: 66,067 articles • Showing 2 of 66,067
pubmed

A biochemical mechanism for Stu2/XMAP215-family microtubule polymerases.

Gangadharan B; Kober DL; Rice LM

Scientists studied how a protein called Stu2 helps microtubules grow by using special parts called TOGs. They found that Stu2 works like an enzyme by speeding up microtubule growth and sticking to tubulin efficiently. This is similar to how another protein helps actin grow, showing how different proteins can work in similar ways.

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pubmed

Complementary vertebrate models exhibit phenotypes relevant to DeSanto-Shinawi Syndrome.

Lee KH; Stafford AM; Pacheco-Vergara M; Cichewicz K; Canales CP; Seban N; Corea M; Rahbarian D; Bonekamp KE; Gillie GR; Pacheco-Cruz D; Gill AM; Hwang HE; Kim YE; Uhl KL; Jager TE; Shinawi M; Li X; Obenaus A; Crandall SR; Jeong J; Nord AS; Kim CH; Vogt D

Researchers are studying a rare disorder called DeSanto-Shinawi Syndrome, which affects brain development and behavior. They created special mouse and fish models to understand the syndrome better. The study found changes similar to those in people with the syndrome, helping scientists learn more about what causes these issues.

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