How IRE1 Protein Changes Shape and Binds with Unfolded Peptides
Spinetti E; Ścibisz G; Karagöz GE; Covino R
When proteins in cells don't fold correctly, it can cause stress. A protein called IRE1 helps detect this problem and starts fixing it. This study used special computer models to show how IRE1 looks at these unfolded proteins and starts the process to help them.