pubmed
Knockdown of a regulatory barcode shifts macrophage polarization destination from M1 to M2 and increases pathogen burden upon infection.
Ravichandran S; Bhatt B; Shah A; Das D; Narayanaswamy Balaji K; Chandra N
Scientists studied how immune cells called macrophages choose different roles when they get different signals. They found three key control proteins that can help change a macrophage from one type, called M1, to another type, called M2, which may help guide immune responses.
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