B cell expression of an enzymatic intermediary in ether lipid biosynthesis promotes antibody responses and germinal center size.
Cho SH; Jones MA; Meyer K; Anderson DM; Chetyrkin S; Calcutt MW; Caprioli RM; Semenkovich CF; Boothby MR
Researchers discovered that a specific enzyme, called PexRAP, is important for B cells to respond better to germs or vaccines. This enzyme helps B cells grow and survive by controlling certain chemicals inside them, leading to stronger and better immune responses.