Condensin and topoisomerases cooperate to relieve topological stress at stalled replication forks.
Da Mota M; Delamarre A; Barthe A; Jackson J; Bouzalmad N; Torán-Vilarrubias A; Lin YL; Ribeyre C; Vindigni A; Pasero P; Lengronne A
Scientists found that a special protein called condensin helps make sure DNA copies correctly in yeast and human cells. Condensin works with other helpers to fix problems when DNA gets tangled during copying. This process is important to stop harmful changes in chromosomes.