Research Articles

Peer-reviewed studies distilled into actionable summaries. Updated daily.

Total: 55,611 articles • Showing 2 of 55,611
pubmed

A RIG-I targeting nanozyme induces PANoptosis for cancer immunotherapy.

Dong S; Yuan Y; Cao H; Zhang M; Liang S; Zhang M; Su X; Luo L; Zhao X; Li L; Xu Q; Li Y; Guo K; Guo X; Shi J; Gao L; Zhang G; Hu S; Chen L

Scientists have found a way to help the immune system fight cancer by using a special tiny tool called Hemin-His-Mn. This tool helps kill cancer cells by starting a process that involves different ways cells can die, and it also makes chemicals that help the body attack cancer. In tests with mice, this method made the immune system work better against cancer.

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pubmed

BCAT1 inhibits crotonate-related epigenetic modulation of metabolic genes in tumor-associated macrophages to counter immunosuppression.

Zhang W; Liang S; Han S; Zha Q; Sun L; Tao S; Zhang Y; Chu J; Chu Q; Zhang N; Ma K; Liu Y; Cui T; Gu X; Cheng C; Guo X; Fu Y; Xing C; Duan J; Long Y; Yang D; Wang J; Liu L

Scientists found that a molecule called BCAT1 is important in controlling certain cells in liver cancer. These cells can either help or hurt the body’s fight against cancer, and changing BCAT1 levels can make treatments work better. This discovery might lead to better ways to treat liver cancer.

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