Heterotypic interfacial tension between oncogenic and wild-type populations forms the mechanical basis of tissue-specific oncogenesis in epithelia.
Datta A; Dewan P; Puthoor AA; Chhabra T; Tejaswi T; Muthukrishnan S; Rao A; Sarkar S; Vishwakarma M
The study explains why a cancer change happens in some body parts but not others. They found that how cells push or pull on each other affects if a cell becomes cancerous in different body tissues. The way these cells act is different, like in breast and lung cells, which helps us understand how cancer might start or grow.