Research Articles

Peer-reviewed studies distilled into actionable summaries. Updated daily.

Total: 51,757 articles • Showing 2 of 51,757
pubmed

A genome-wide MAGIC kit for recombinase-independent mosaic analysis in .

Shen Y; Yeung AT; Ditchfield P; Korn E; Clements R; Chen X; Wang B; Huang Z; Sheen M; Jarman PA; Han C

Scientists developed a new tool called MAGIC to study how cells grow and change without needing extra parts added to the DNA. They created a special kit to make MAGIC work better in different cells, helping us learn more about genes and how they work in many types of animals.

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pubmed

Multiple modes of cholesterol translocation in the human Smoothened receptor.

Bansal PD; Kinnebrew M; Rohatgi R; Shukla D

Smoothened (SMO) is a special protein that helps in sending signals inside the cell and is connected to diseases like cancer. It helps move cholesterol within the cell, which is important for making new cancer treatments. The study found that cholesterol can move through SMO in two ways, and it explains how this process works.

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