How a Protein Helps Control Metabolism by Stabilizing Filament Formation
Greene E; Muniz R; Yamamura H; Hoff SE; Bajaj P; Tecson MCB; Geluz C; Lee DJ; Thompson EM; Arada A; Lee GM; Bonomi M; Kollman JM; Fraser JS
The study found that an enzyme called glutamine synthetase can change its shape to form filaments when there is a lot of glutamine. This change makes the enzyme work less well with ammonia. By changing shape, the enzyme controls how much work it does based on how much glutamine is around.