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pubmed
SerpinB7 promotes c-Myc-mediated glycolysis by interacting with ANXA2 to facilitate the progression of non-small cell lung cancer.
Zhao F; Zeng F; Zhou P; Zheng H; Hu Y; Tang J; Hu Y; Li G; Feng Y; Wang X; Yu J; Li Y; Yue C; Liu X; Zhang T; Huang N; Sun X; Wang X; Huang S; He M; Zeng X; Wu W; Cui X; Cui K; Li J
In lung cancer, a protein called SerpinB7 was found to help cancer cells use sugar in a bad way, which makes the cancer grow worse. SerpinB7 works with other proteins to keep this sugar process going, and when scientists blocked SerpinB7, the cancer didn't grow as much. This means SerpinB7 might be important for stopping this kind of cancer.
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pubmed
Plasma proteome-metabolome signatures enable non-invasive early detection and lymph node risk stratification in breast cancer.
Zhang W; Yao Y; Wang Y; Shen L; Ding J; Zhu Y; Xu H; Shao Y; Gu X; Lu H; Zhou J; Deng H; Zhou J; Chen W; Xia W; Jiang J; Yu X; Sun S; Chen J; Liu J; Wang D; Liu W; Lin Z; Xu K; Wu Q; Huang J; Li H; Yu Z; Ni C
Scientists found a new way to find breast cancer early using a special blood test. This method looks at many different proteins and tiny chemicals in the blood to tell if a person has cancer, and it works well even when other tests might not show it clearly. This new test helps doctors find and understand breast cancer better without needing to do surgery.
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