Shifting AAV9 tropism by binding moiety insertion enhances transduction of tumor cell lines and human glioblastoma explants.
Rothschild-Gronau C; Borchert P; Radukic MT; Haverkamp L; Coras R; Simon M; Müller KM
Scientists are trying to make better cancer treatments, especially for a tough brain cancer called glioblastoma. They used tiny viruses to deliver special proteins to target cancer cells more accurately. Some of these viruses worked well in lab tests and might help create better treatments in the future.