Research Articles

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Total: 39,851 articles • Showing 2 of 39,851
pubmed

Peripheral glia and neurons jointly regulate activity-induced synaptic remodeling at the neuromuscular junction.

Chang YC; Peng YJ; Lee JY; Wen A; Chang KT

Neurons and glial cells work together to help the brain change and grow by adjusting how they connect. Glial cells use a protein called Shv to help this process by controlling how much Shv is outside the neurons and keeping a balance of important chemicals. This teamwork helps the brain's connections stay strong and flexible.

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pubmed

PTBP1 depletion in mature astrocytes reveals distinct splicing alterations without neuronal features.

Zhang M; Kubota N; Nikom D; Arient A; Zheng S

Scientists studied if turning off a specific gene, PTBP1, in brain cells called astrocytes could change them into neuron cells. They found that stopping PTBP1 didn't cause many astrocytes to become neurons; instead, it changed the cells in a different way. This means that just targeting PTBP1 isn't enough to make brain support cells become neuron cells.

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