Peptide-based covalent inhibitor of tubulin detyrosination promotes mesenchymal-to-epithelial transition in lung cancer cells.
Impheng H; Gillard G; Numnoi N; Feral A; Simon M; Louet M; Amblard M; Juge F; Vezenkov L; Rogowski K
Scientists found a way to stop a special process in cells that helps cancer grow and spread. They made a new medicine that can block this process, and they hope it could be a new way to fight cancer. When they tested it on lung cancer cells, the cells couldn't move well or form tiny ball-like shapes, which might make the cancer less dangerous.