Research Articles

Peer-reviewed studies distilled into actionable summaries. Updated daily.

Total: 52,373 articles • Showing 2 of 52,373
pubmed

Structural basis for prostaglandin and drug transport via SLCO2A1.

Joshi C; Deme JC; Nakamura Y; Hsu WT; Goult JD; Kato T; Parker JL; Biggin PC; Lea SM; Nakanishi T; Newstead S

Scientists studied a protein called SLCO2A1 that helps move substances like medicines through the body. They discovered important details about how this protein works with certain drugs and molecules by using special imaging and testing methods. This helps us understand better how these proteins choose what to transport.

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pubmed

Dalpiciclib plus chidamide in HR + /HER2-advanced breast cancer after CDK4/6 inhibitor failure: a phase Ib trial.

Zhou J; Wu X; Du Y; Xiao J; Kang X; Chen J; Wang X; Tai Y; Bian L; Zhang S; Pang Z; Li Y; Jiang Z; Xu X; Wang T

Scientists tested a new treatment for a type of breast cancer, using two medicines called dalpiciclib and chidamide. They found that this treatment could help some patients, and they are looking at how safe it is and how well it works. Some people had side effects like fewer white blood cells, but overall the treatment showed promise.

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