CBP phosphorylation maintains intestinal homeostasis by supporting the stem cell niche through versican.
Lin YT; Liu C; Hsu YH; Miaw SC; Wu MS; Chen CC
Scientists found out that when a protein called CBP doesn't work right, it can cause problems in the gut. It changes what CBP sticks to, leading to fewer cells growing in the intestines. They discovered how fixing CBP or adding something called versican can help, and this might be important for treating gut diseases like colitis.