Research Articles

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Total: 62,225 articles • Showing 2 of 62,225
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How PHD1 Enzyme Changes RepoMan to Affect Cell Division

Druker J; Jiang H; Shakir D; Child F; Alvarez V; Platani M; Corno A; Alabert C; Saurin AT; Swedlow JR; Rocha S; Lamond AI

Scientists discovered a special way to look at a tiny part of proteins that helps cells divide correctly. They found out that an important protein, RepoMan, needs a little change at one spot to work properly with other cell parts. If this change doesn't happen, cells can have problems dividing and may even die.

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How Proline Hydroxylation is Analyzed Using Advanced Lab Techniques

Jiang H; Druker J; Wilson JW; Bensaddek D; Swedlow JR; Rocha S; Lamond AI

The researchers created a new method to find special parts in proteins called proline hydroxylation sites. They used a special type of testing to find these sites in two different cell types. Some of these sites are important for things the cells do, like handling RNA and controlling when cells grow.

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