Research Articles

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pubmed

Higher GATA4 Levels in Aging Cartilage Tied to Poor Cartilage Repair and Arthritis

Makarczyk MJ; Zhang Y; Aguglia A; Bartholomew O; Hines S; Li K; Sinkar S; Liu S; Duvall C; Lin H

Scientists studied how aging is related to osteoarthritis and found that a protein called GATA4 is important. They discovered GATA4 is higher in older cells and may help make cartilage stronger. By reducing GATA4, they could help improve cartilage health and reduce symptoms of osteoarthritis.

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pubmed

Improving Virus Delivery to Cancer and Brain Tumor Cells by Adding a New Binding Part

Rothschild-Gronau C; Borchert P; Radukic MT; Haverkamp L; Coras R; Simon M; Müller KM

Scientists are trying to make better cancer treatments, especially for a tough brain cancer called glioblastoma. They used tiny viruses to deliver special proteins to target cancer cells more accurately. Some of these viruses worked well in lab tests and might help create better treatments in the future.

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