Research Articles

Peer-reviewed studies distilled into actionable summaries. Updated daily.

Total: 68,301 articles • Showing 2 of 68,301
pubmed

The transcription factor BCL11A restores differentiation potential to aged oligodendrocyte progenitor cells.

Ghosh T; Baror R; Zhao C; Sharma A; Au WH; Lakatos A; Goldman N; Franklin RJM

Scientists found that aging makes special brain cells called OPCs less able to turn into myelin-making cells. By studying gene patterns, they found a key factor whose boost helped old OPCs work better again and improve repair after injury.

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pubmed

Improved cryo-EM reconstruction of sub-50 kDa complexes using 2D template matching.

Zhang K; Grant T; Grigorieff N

Scientists found a better way to see very small proteins with cryo-EM, a tool that helps make 3D pictures of tiny body parts. Their method helped them study a hard-to-see protein and its drug site more clearly, and it may help with even smaller targets in future research.

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