Research Articles

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Total: 51,744 articles • Showing 2 of 51,744
pubmed

Defining the chromatin-associated protein landscapes on repetitive elements using synthetic TALE proteins.

Carloni R; Devlin T; Tong P; Spanos C; Auchynnikava T; Rappsilber J; Matthews KR; Allshire RC

Kinetoplastids are special kinds of eukaryotes that are different from others like plants and animals. Their DNA has many repeating patterns that help them change and survive better. Scientists used special tools to learn more about these repeating patterns and found out new things about how the DNA is organized and how it helps them stay healthy and avoid attackers.

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pubmed

long noncoding RNA acts in both - and -acting transcriptional regulation and controls nucleolar biology.

Monziani A; Unfried JP; Cvetanovic T; Ulitsky I

Mammalian genomes have something called long noncoding RNAs (lncRNAs) that scientists are still trying to understand. Researchers looked at a specific lncRNA in breast cancer cells and found it helps control other genes and important processes in the cell. This lncRNA works in different ways to help keep the cell running properly.

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