In situ mutational screening and CRISPR interference define cis-regulatory inputs during compartment boundary formation.
Aguilar G; Sickmann ME; Bieli D; Born G; Affolter M; Müller M
Scientists studied how certain genes help shape a fly's wing during its early growth. They found that when one gene called apE is not working right, the wings can grow incorrectly, often producing two similar wing parts. They also discovered which proteins work with apE to help create correctly formed wings.