Research Articles

Peer-reviewed studies distilled into actionable summaries. Updated daily.

Total: 41,466 articles • Showing 2 of 41,466
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Extracellular Vesicles Define Discrete Nano-Based Niches Within the Human Haematopoietic System.

Grenier-Pleau IJ; Wells CJ; Holmes SM; Hall C; Vermeulen M; de Villiers CA; Penders J; Pedersen SV; Dick SA; Bonneil E; Slobodyanyuk M; Nagree MS; Kaur J; McNaughton AJM; Beaulieu J; Stevens MM; Xie SZ; Rauh MJ; Postovit LM; Knapp DJHF; Reimand J; Tyryshkin K; Thibault P; Craig AW; Rudan JF; Mann S; Chan EYW; Abraham SA

This study looks at special areas in the bone where important stem cells for blood and immunity live. It found that small particles help these areas work well by sending specific signals to the stem cells. These findings highlight how these small particles help in blood production and immunity.

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Modeling CIC::DUX4 sarcoma reveals oncogene-mediated MHCI-dependent immune evasion.

Vachanaram AR; Wei E; Mitanoska A; Bassett W; Kyba M; Bosnakovski D

Researchers created a special mouse model to study a type of cancer called CIC::DUX4 sarcoma. This model helps them understand how the cancer grows, how it avoids the immune system, and ways to stop it using new treatments. They found that stopping a specific protein or using certain drugs can help the immune system fight the cancer better.

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