pubmed
How L-type Pyocins Kill Bacteria Without Entering the Cell
Munder F; Johnson MD; Samuels I; McCaughey L; Zdorevskyi O; Wang C; Kropp A; Zavan L; Price EP; Sarovich DS; Varshney S; McDevitt CA; Venugopal H; Sharma V; Doyle MT; Short F; Ghosal D; Connolly JPR; Knott GJ; Grinter R
Some bacteria are hard to kill with regular antibiotics because of their strong protective walls. Scientists found that special protein antibiotics, called L-type pyocins, can stop these bacteria by blocking a part of their outer wall called the BAM complex, causing the bacteria to die. This discovery could help make new kinds of antibiotics.
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