Research Articles

Peer-reviewed studies distilled into actionable summaries. Updated daily.

Total: 68,504 articles • Showing 2 of 68,504
pubmed

How Serotonin Affects Cancer: Metabolism, Gene Control, and the Immune System

Zhu J; Bai J; An L; Zhang C

Serotonin is a body chemical that can help cancer cells grow, change, and resist treatment. It can also affect the immune cells around a tumor, which may change how well cancer treatments work.

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pubmed

A CCL21 Gene-Modified Dendritic Cell Vaccine Combined With Pembrolizumab for Advanced Non-Small Cell Lung Cancer: A Phase 1 Trial

Oh MS; Lisberg AE; Dumitras C; Tran LM; Salehi-Rad R; Krysan K; Lim RJ; Shabihkhani M; Romero T; Li S; Zeng W; Jing Z; Li R; Kahangi BP; Tsvetkova O; Suh RD; Abtin F; Genshaft SJ; Oh SS; Fishbein GA; Greenwald DR; Kahlon KS; Anand SR; Ashouri S; Goldman JW; Lee JM; Zhou XJ; Elashoff DA; Garon EB; Liu B; Dubinett SM

A study tested a new cancer vaccine with pembrolizumab in people with advanced lung cancer. The treatment was safe and helped more immune cells enter tumors, but it did not shrink tumors or work well enough overall.

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