DCAF11-dependent molecular glue degrader activated by glutathionylation.
Yoon H; Wachter F; Barrett KA; Jin C; Rodríguez-Pöhnlein A; Rutter JC; Lumpkin RJ; Metivier RJ; Donovan KA; Baek K; Jiang Y; Lee M; Kalis RW; Che J; Xiong Y; Fischer ES; Ebert BL
Scientists found a new way to get rid of bad proteins in the body. They discovered a special helper called M12 that helps destroy a protein called DDX18 by using another protein, DCAF11. This could help treat diseases.