How PKD2L1 Channels in Brain Neurons Detect pH Levels in Spinal Fluid
Vitar M; Prieto D; Malas S; Russo RE; Trigo FF
Cerebrospinal fluid-contacting neurons (CSFcNs) are special cells in the spinal cord that help sense changes in the fluid around the brain and spine. They have unique parts inside the spinal cord that detect changes in things like pH levels using channels called PKD2L1. The study found that these channels make the cells sensitive and help them respond to different signals.