Research Articles

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pubmed

Identification of the regulatory elements and protein substrates of lysine acetoacetylation.

Fu Q; Nguyen T; Kumar B; Azadi P; Zheng YG

Scientists have found a new way to detect a special mark on proteins in cells, called Kacac, which comes from a molecule named acetoacetate. They also found out which proteins can add or remove this mark and discovered it affects many processes inside cells. This discovery helps us understand more about how certain body processes work and could help in future studies.

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pubmed

Subregional activity in the dentate gyrus is amplified during elevated cognitive demands.

Castillon C; Otsuka S; Armstrong JN; Contractor A

The study looked at how mouse brain cells in a part called the dentate gyrus work when the brain has to do harder thinking tasks. They found that as the tasks got harder, certain brain cells were more active in a specific area and this helped mice tell apart similar places. When these brain cells were blocked, the mice had trouble with the task.

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