Research Articles

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Total: 64,963 articles • Showing 2 of 64,963
pubmed

Reprogramming of host energy metabolism mediated by the TNF-iNOS-HIF-1α axis plays a key role in host resistance to infection.

Matteucci KC; Leite NPS; Assis PA; Hirako IC; Pioto F; Ojelabi O; Toller-Kawahisa JE; Vaz LG; Costa DL; da Silva JS; Alves-Filho JC; Gazzinelli RT

The study found that TNF helps the body fight infections by controlling energy and sugar use, but it also makes mice feel sick and less active. TNF is needed for special cells in the body to work properly and fight off infections.

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pubmed

Active dendrites enable robust spiking computations despite timing jitter.

Burger TSJ; Rule ME; O'Leary T

Dendritic action potentials last a long time, much longer than other nerve signals. This helps them collect information better, even if it comes at different times. This way of working could help with quick decisions and can teach us about how the brain works and help make new technology.

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