How Placental TRPV2 Protein Supports Fetal Development
De Clercq K; Pérez-García V; Panda A; Gevaert S; Witvrouwen J; Van Mechelen P; Lopez-Tello J; Maksym K; David AL; Van Den Broeck E; Luyten K; Segal A; Poovathingal S; Wojno M; Katanosaka Y; Vennekens R; Pasque V; Sferruzzi-Perri AN; Voets T; Vriens J
This study found that the TRPV2 channel is important for helping the placenta develop properly and for determining how big and healthy a baby can grow. When TRPV2 was missing, it caused problems in the placenta, slowing down baby growth and leading to problems in pregnancies. The research showed that TRPV2 helps certain cells in the placenta develop and is also important in human placenta development.