Research Articles

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Total: 53,039 articles • Showing 2 of 53,039
pubmed

CBP phosphorylation maintains intestinal homeostasis by supporting the stem cell niche through versican.

Lin YT; Liu C; Hsu YH; Miaw SC; Wu MS; Chen CC

Scientists found out that when a protein called CBP doesn't work right, it can cause problems in the gut. It changes what CBP sticks to, leading to fewer cells growing in the intestines. They discovered how fixing CBP or adding something called versican can help, and this might be important for treating gut diseases like colitis.

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pubmed

Neoantigen evolution and response to checkpoint inhibitor immunotherapy in colorectal cancer.

Sholokhova A; Kaveh K; Bozic I

This research looks at how well a certain kind of cancer treatment works. The study focuses on a type of cancer called colorectal cancer and tries to understand why not everyone gets the same results from the treatment. It finds that having certain strong markers, called neoantigens, on cancer cells can help medicines work better.

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