Research Articles

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pubmed

Identifying TMEM263 as an Endoplasmic Reticulum Protein That Helps Control the Early Formation of Fat Droplets

Yalci K; Chala N; Moss J; MacDonald C; Zakrzewski P; Smith P; Sevil R; Willoughby L; Wonklyn S; Andrews T; Hammond CL; Corey RA; Carroll B

Scientists found a protein called TMEM263 that helps cells make and store fat droplets. When this protein is missing, cells and zebrafish cannot grow well, which can cause small body size and growth problems.

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pubmed

A deep learning method for modeling T-cell receptor, peptide, and HLA interactions

Cao K; Li R; Stražar M; Brown EM; Nguyen PNU; Pust MM; Park J; Graham DB; Ashenberg O; Uhler C; Xavier RJ

Scientists made a new computer tool called StriMap that can better predict how T cells recognize tiny pieces of germs or body cells. It worked very well and helped find a bacterial peptide that can turn on certain T cells, which may help explain some autoimmune diseases like ankylosing spondylitis and inflammatory bowel disease.

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