Research Articles

Peer-reviewed studies distilled into actionable summaries. Updated daily.

Total: 49,193 articles • Showing 2 of 49,193
pubmed

Nonlinear transcriptional responses to gradual modulation of transcription factor dosage.

Domingo J; Minaeva M; Morris JA; Ghatan S; Ziosi M; Sanjana NE; Lappalainen T

The study looked at changing how much certain genes are turned on or off in cells to understand how this affects the cells and traits. They used a special tool to slowly change gene activity and found that adjusting this can change many other genes in surprising ways. This helps scientists learn more about how gene changes relate to diseases.

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pubmed

Intratumoral microbiome: the double-edged sword in remodeling cancer immunotherapy.

Yan D; Yu Y; Liang C; Cui Z; Shi L; Li G; Ren C

Scientists found that tiny living things called microbes in tumors can make cancer treatments work better or worse. Some of these microbes can stop the body from fighting cancer, while others can help new treatments work better against cancer. This research helps in finding new ways to make cancer treatments more effective.

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