Research Articles

Peer-reviewed studies distilled into actionable summaries. Updated daily.

Total: 58,718 articles • Showing 2 of 58,718
pubmed

HSD17B7 is required for the function of sensory hair cells by regulating cholesterol synthesis.

Shen Y; Wang Z; Wang X; Qian F; Zhong M; Wang X; Cheng J; Liu D

Cholesterol is important for our bodies, and this study looks at a special step in making cholesterol that is important for hearing. A problem with a gene called HSD17B7 can lead to hearing loss because it affects how cells in the ear work. The study shows that this gene is important for cholesterol in ear cells, which helps with hearing.

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pubmed

MiR-494-5p suppresses colorectal cancer metastasis by multi-level targeting of KAT2B, a novel mechanism disrupting KAT2B enhancer-promoter looping, and inhibiting c-JUN-driven pro-metastatic properties.

Chen S; Leupold JH; Patil NS; Xu P; Wang X; Hu X; Allgayer H

Scientists are trying to understand how colorectal cancer spreads, which is why it is hard to treat. They are studying tiny molecules called microRNAs that might play a big role in this process, but they still have a lot to learn.

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