Beta-Glucan modulates monocyte plasticity and differentiation capacity to mitigate DSS-induced colitis.
Lv Y; Fan Y; Gao Q; Chen Q; Hu Y; Wang L; Shi H; Chen E; Xu Q; Cai Y; Fan Q; Li L; Du D; Ren J; Cheng SC; Xu H
The study found that a substance called β-glucan can train certain immune cells to help protect against a type of gut inflammation called colitis. This training helps the immune cells fight infections better and heal the gut faster, and this protection can even be passed to other mice. The results suggest that this approach might help treat human conditions like inflammatory bowel disease in the future.