Research Articles

Peer-reviewed studies distilled into actionable summaries. Updated daily.

Total: 54,560 articles • Showing 2 of 54,560
pubmed

HEB collaborates with TCR signaling to upregulate and enable γδT17 cell maturation in the fetal thymus.

Selvaratnam JS; da Rocha JDB; Rajan V; Wang H; Reddy EC; Gams MS; Liu JJ; Murre C; Wiest D; Guidos CJ; Zúñiga-Pflücker JC; Anderson MK

Researchers found that certain signals help T cells, a type of immune cell, grow and do their job, like making IL-17, a substance the body uses to fight off infections. They studied mice with different genetic changes and saw that certain proteins must work together to make these T cells fully grow and do their job properly. They learned more about how T cells grow by looking at these important signals and how they help T cells fight germs better.

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pubmed

Multiple functions of cerebello-thalamic neurons in learning and offline consolidation of a motor skill in mice.

Varani AP; Mailhes-Hamon C; Sala RW; Sarraudy M; Fouda S; Frontera JL; Léna C; Popa D

Learning new motor skills takes time and uses parts of the brain like the cortex, basal ganglia, and cerebellum. In a study with mice, scientists found that different cerebellar neurons help with learning some parts of a skill while others help with remembering it after practice. Both types of neurons are needed to get really good at the new skill.

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