SMYD2 regulates lymph node metastasis derived from intrahepatic cholangiocellular carcinoma through CCR7-dependent chemotaxis.
Nakamura M; Hayami S; Miyamoto A; Suzaki N; Yoshimura T; Nakamura K; Shigekawa Y; Shimizu A; Kitahata Y; Takeuchi A; Motobayashi H; Matsumoto K; Ehata S; Hamamoto R; Kawai M
Scientists are studying a protein called SMYD2 to see how it affects cancer that spreads to the lymph nodes. They found that when SMYD2 is less active, cancer cells don't grow or move as much. This discovery might help explain how the cancer spreads and could lead to new treatments.