pubmed
Heterogeneity of Sonic Hedgehog response dynamics and fate specification in single neural progenitors.
Xiong F; Tentner AR; Nandagopal S; Hiscock TW; Huang P; Tsung-Megason SG
Scientists studied how cells in zebrafish respond to a signal called Sonic hedgehog, which helps cells decide their future jobs. They found that cells react differently to the signal, and this makes it hard to predict exactly what job each cell will take. The research shows that the way cells understand these signals isn’t always very exact, especially in certain parts of the developing fish.
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